Acute changes in histopathology and intravascular imaging after catheter-based renal denervation in a porcine model
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چکیده
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Renal sympathetic nerve activity after catheter-based renal denervation
BACKGROUND Catheter-based renal sympathetic denervation (RDN) has been considered a potential treatment for therapy resistant hypertension (RHT). However, in a randomized placebo-controlled trial, RDN did not lead to a substantial blood pressure (BP) reduction. We hypothesized that variation in the reported RDN efficacy might be explained by incomplete nerve disruption as assessed by renal 123I...
متن کاملRenal Denervation Renal Hemodynamics and Renal Function After Catheter-Based Renal Sympathetic Denervation in Patients With Resistant Hypertension
Increased renal resistive index and urinary albumin excretion are markers of hypertensive end-organ damage and renal vasoconstriction involving increased sympathetic activity. Catheter-based sympathetic renal denervation (RD) offers a new approach to reduce renal sympathetic activity and blood pressure in resistant hypertension. The influence of RD on renal hemodynamics, renal function, and uri...
متن کاملRenal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension.
Increased renal resistive index and urinary albumin excretion are markers of hypertensive end-organ damage and renal vasoconstriction involving increased sympathetic activity. Catheter-based sympathetic renal denervation (RD) offers a new approach to reduce renal sympathetic activity and blood pressure in resistant hypertension. The influence of RD on renal hemodynamics, renal function, and uri...
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ژورنال
عنوان ژورنال: Catheterization and Cardiovascular Interventions
سال: 2017
ISSN: 1522-1946
DOI: 10.1002/ccd.27158